Here you can find protocols, datasets, and other resources developed by our lab.
SPIDR is a multiplexed method to generate RBP-RNA binding maps. An up-to-date protocol can be downloaded at the link below.
Download SPIDR ProtocolSPADE is a Python tool for analyzing SEC-MS (Size Exclusion Chromatography coupled with Mass Spectrometry) data to evaluate protein assembly state dynamics across multiple samples. This is the version used for the SEC-MX paper.
View SPADE on GitHubThis is a pipeline for processing SPIDR sequencing data. The pipeline turns SPIDR fastq files into 1 BAM per RBP in the experiment along with some supplementary bam files for reads that did not meet cutoffs. The README on GitHub has more information.
View SPIDR on GitHubThe link below contains supplemental tables referenced in the main SPIDR manuscript.
Access SPIDR Supplemental Data